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产品详情
| 名称： | anti- Histone-H3 antibody |
|---|---|
| 货号 ： | FNab03890 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格 ： | 100ug(微克) |
| 状态 ： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原 ： | histone cluster 2, H3a |
| 免疫原别称 ： | H3/n antibody, H3/o antibody, H3F2 antibody, H3FM antibody, HIST2H3A antibody, HIST2H3C antibody, HIST2H3D antibody, histone cluster 2 antibody, H3a antibody, Histone H3 antibody, Histone H3.2 antibody, Histone H3/m antibody, Histone H3/o antibo |
| 分子量： | 15-17 kDa |
| 验证应用： | ELISA, WB, IHC, IF |
| 建议稀释比例： | WB: 1:500-1:5000; IHC: 1:50-1:200; IF: 1:20-1:200 |
| UniProt ID ： | Q71DI3 |
| 克隆性 ： | 多克隆 |
| 背景介绍 ： | HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. |
| 图像： |  Immunofluorescent analysis of HEK-293 cells using FNab03890 (Histone-H3 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG。  Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03890(Histone-H3 Antibody) at dilution of 1:50。  MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03890(Histone-H3 antibody) at dilution of 1:1000。 |
