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发布时间：2023-08-30 14:06 咨询量：
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产品详情
| 名称 ： | anti- PARP1 antibody |
|---|---|
| 货号： | FNab06151 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格 ： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法 ： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型 ： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | poly (ADP-ribose) polymerase 1 |
| 免疫原别称 ： | ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, pADPRT 1 antibody, PARP antibody, PARP 1 antibody, PARP1 antibody, poly (ADP ribose) polymerase 1 antibody, Poly [ADP ribose] polymerase 1 antibody, Poly[ADP ribose] synthase 1 antibody, PPOL an |
| 分子量 ： | 115 kDa |
| 验证应用 ： | ELISA, WB, IHC, IF |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| UniProt ID ： | P09874 |
| 克隆性 ： | 多克隆 |
| 背景介绍： | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
| 图像： |  Immunohistochemistry of paraffin-embedded human breast cancer using FNab06151(PARP1 antibody) at dilution of 1:100 。
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