服务热线
18062437365
名称: | anti- Chk1 antibody |
---|---|
货号: | FNab01653 |
适应种属: | 人源,大鼠,小鼠 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 蛋白A/G柱纯化 |
纯度: | 经SDS-PAGE分析,纯度大于95% |
宿主: | 小鼠 |
亚型: | IgG2a |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | CHK1 checkpoint homolog |
免疫原别称: | CHEK1 antibody, Chk1 antibody |
分子量: | 50 kDa |
验证应用: | ELISA, WB, IHC |
建议稀释比例: | WB: 1:500-1:2000; IHC: 1:20-1:200 |
UniProt ID: | O14757 |
克隆性: | 单克隆 |
背景介绍: | HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa. |
图像: | Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab01653(CHK1 Antibody) at dilution of 1:50。
|