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产品详情
| 名称： | anti- PDCD6IP antibody |
|---|---|
| 货号 ： | FNab06243 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态 ： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原 ： | programmed cell death 6 interacting protein |
| 免疫原别称： | AIP1 antibody, ALG 2 interacting protein 1 antibody, Alix antibody, DRIP4 antibody, HP95 antibody, KIAA1375 antibody, PDCD6 interacting protein antibody, PDCD6IP antibody |
| 分子量： | 100 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例 ： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| UniProt ID： | Q8WUM4 |
| 克隆性： | 多克隆 |
| 背景介绍 ： | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. |
| 图像： |  Immunohistochemistry of paraffin-embedded rat kidney using FNab06243( PDCD6IP antibody) at dilution of 1:100 。
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