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产品详情
| 名称： | anti- HSP70 antibody |
|---|---|
| 货号： | FNab04048 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态 ： | 液体 |
| 纯化方法 ： | 免疫亲和纯化 |
| 纯度 ： | 经SDS-PAGE分析,纯度大于95% |
| 宿主 ： | 兔 |
| 亚型： | lgG |
| 存储 ： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | heat shock 70kDa protein 1A |
| 免疫原别称： | Heat shock 70 kDa protein 1A antibody, HSPA1A antibody, Heat shock 70 kDa protein 1 antibody, HSP70-1 antibody, HSPA1 antibody, HSX70 antibody |
| 分子量： | 66-70 kDa |
| 验证应用： | ELISA, IHC, WB, IF, FC, IP |
| 建议稀释比例 ： | WB: 1:1000-1:10000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| UniProt ID： | P0DMV8 |
| 克隆性： | 多克隆 |
| 背景介绍： | HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines. |
| 图像： |  Immunofluorescent analysis of HepG2 cells, using HSPA1A antibody FNab04048 at 1:50 dilution. Blue pseudocolor = DAPI (fluorescent DNA dye)。
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