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      发布时间 :2024-02-04 16:54   咨询量 :
    1. 英文名称:anti- Vimentin antibody
    2. 产品货号: FNab09410
    3. 适应种属 :人源,大鼠,小鼠
    4. 宿主:小鼠
    5. 亚型: IgG1
    6. 验证应用  : ELISA, WB, IHC
    7. 简介:js3333线路检测中心生物抗Vimentin抗体经SDS-PAGE分析 ,纯度大于95% ,采用蛋白A/G柱纯化方法 ,为用户提供高亲和力、高特异性的优质抗体。
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      产品详情
      名称:anti- Vimentin antibody
      货号: FNab09410
      适应种属 :人源,大鼠,小鼠
      规格:100ug(微克)
      状态:液体
      纯化方法:蛋白A/G柱纯化
      纯度:经SDS-PAGE分析,纯度大于95%
      宿主:小鼠
      亚型: IgG1
      存储:用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
      免疫原 : vimentin
      免疫原别称: FLJ36605 antibody, VIM antibody, Vimentin antibody
      分子量: 55 kDa
      验证应用: ELISA, WB, IHC
      建议稀释比例: WB: 1:1000-1:10000; IHC: 1:200-1:2000; IF: 1:20-1:200
      UniProt ID: P08670
      克隆性 :单克隆
      背景介绍 :Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
      图像:     Vimentin抗体
      Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab09410(Vimentin Antibody) at dilution of 1:500 。
          anti- Vimentin antibody
      Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09410(Vimentin Antibody) at dilution of 1:2000。
      

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